Immunogenicity and Protective Efficacy of Influenza A DNA Vaccines Encoding Artificial Antigens Based on Conservative Hemagglutinin Stem Region and M2 Protein in Mice

Background: Development of a universal vaccine capable to induce antibody responses against a broad range of influenza virus strains attracts growing attention. Hemagglutinin stem and the exposed fragment of influenza virus M2 protein are promising targets for induction of cross-protective humoral a...

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Vydáno v:Vaccines (Basel)
Hlavní autoři: Bazhan, Sergei, Antonets, Denis, Starostina, Ekaterina, Ilyicheva, Tatyana, Kaplina, Olga, Marchenko, Vasiliy, Durymanov, Alexander, Oreshkova, Svetlana, Karpenko, Larisa
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565880/
https://ncbi.nlm.nih.gov/pubmed/32784907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8030448
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