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Identification of MicroRNA-Related Tumorigenesis Variants and Genes in the Cancer Genome Atlas (TCGA) Data

MicroRNAs (miRNAs) are a class of small non-coding RNA that can down-regulate their targets by selectively binding to the 3′ untranslated region (3′UTR) of most messenger RNAs (mRNAs) in the human genome. Single nucleotide variants (SNVs) located in miRNA target sites (MTS) can disrupt the binding o...

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Bibliografiske detaljer
Udgivet i:Genes (Basel)
Main Authors: Li, Chang, Wu, Brian, Han, Han, Zhao, Jeff, Bai, Yongsheng, Liu, Xiaoming
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565843/
https://ncbi.nlm.nih.gov/pubmed/32824926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes11090953
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