Biotherapy of Brain Tumors with Phosphatidylserine-Targeted Radioiodinated SapC-DOPS Nanovesicles

Glioblastoma multiforme (GBM), a common type of brain cancer, has a very poor prognosis. In general, viable GBM cells exhibit elevated phosphatidylserine (PS) on their membrane surface compared to healthy cells. We have developed a drug, saposin C-dioleoylphosphatidylserine (SapC-DOPS), that selecti...

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Publicado en:Cells
Autores principales: Davis, Harold W., Vallabhapurapu, Subrahmanya D., Chu, Zhengtao, Wyder, Michael A., Greis, Kenneth D., Fannin, Venette, Sun, Ying, Desai, Pankaj B., Pak, Koon Y., Gray, Brian D., Qi, Xiaoyang
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7565346/
https://ncbi.nlm.nih.gov/pubmed/32854321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9091960
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