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Explorative Combined Lipid and Transcriptomic Profiling of Substantia Nigra and Putamen in Parkinson’s Disease

Parkinson’s disease (PD) is characterized by the loss of dopaminergic neurons from the substantia nigra (SN) that project to the dorsal striatum (caudate-putamen). To better understand the molecular mechanisms underlying PD, we performed combined lipid profiling and RNA sequencing of SN and putamen...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Xicoy, Helena, Brouwers, Jos F., Wieringa, Bé, Martens, Gerard J. M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564986/
https://ncbi.nlm.nih.gov/pubmed/32858884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9091966
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