Explorative Combined Lipid and Transcriptomic Profiling of Substantia Nigra and Putamen in Parkinson’s Disease

Parkinson’s disease (PD) is characterized by the loss of dopaminergic neurons from the substantia nigra (SN) that project to the dorsal striatum (caudate-putamen). To better understand the molecular mechanisms underlying PD, we performed combined lipid profiling and RNA sequencing of SN and putamen...

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Detalhes bibliográficos
Main Authors: Helena Xicoy, Jos F. Brouwers, Bé Wieringa, Gerard J. M. Martens
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-08-01
Colecção:Cells
Assuntos:
Parkinson’s disease
RNA sequencing
transcriptomics
lipidomics
substantia nigra
putamen
Acesso em linha:https://www.mdpi.com/2073-4409/9/9/1966
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