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CRISPR/Cas9 genome editing throws descriptive 3-D genome folding studies for a loop
CRISPR/Cas9 genome editing studies have recently shed new light into the causal link between the linear DNA sequence and 3-D chromatin architecture. Here we describe current models for the folding of genomes into a nested hierarchy of higher-order structures and discuss new insights into the organiz...
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| Опубликовано в: : | Wiley Interdiscip Rev Syst Biol Med |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7564889/ https://ncbi.nlm.nih.gov/pubmed/27265842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/wsbm.1338 |
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