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A Systematic Review of Genotype–Phenotype Correlation across Cohorts Having Causal Mutations of Different Genes in ALS

Amyotrophic lateral sclerosis is a rare and fatal neurodegenerative disease characterised by progressive deterioration of upper and lower motor neurons that eventually culminates in severe muscle atrophy, respiratory failure and death. There is a concerning lack of understanding regarding the mechan...

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Detalhes bibliográficos
Publicado no:J Pers Med
Main Authors: Connolly, Owen, Le Gall, Laura, McCluskey, Gavin, Donaghy, Colette G, Duddy, William J, Duguez, Stephanie
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564886/
https://ncbi.nlm.nih.gov/pubmed/32610599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jpm10030058
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