Hormonal Receptor Status Determines Prognostic Significance of FGFR2 in Invasive Breast Carcinoma

SIMPLE SUMMARY: FGFR2-ER-PR crosstalk leads to hormone-independent progression of breast cancer. In vitro, FGFR2 stimulates PR transcriptional activity and mediates resistance to anti-ER therapies. The postulated poor prognostic effect of FGFR2 overexpression has not been confirmed at clinical level...

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Publicado en:Cancers (Basel)
Autores principales: Braun, Marcin, Piasecka, Dominika, Tomasik, Bartlomiej, Mieczkowski, Kamil, Stawiski, Konrad, Zielinska, Aleksandra, Kopczynski, Janusz, Nejc, Dariusz, Kordek, Radzislaw, Sadej, Rafal, Romanska, Hanna M.
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564845/
https://ncbi.nlm.nih.gov/pubmed/32971804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12092713
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