Upregulation of HIF1-α via an NF-κB/COX2 pathway confers proliferative dominance of HER2-negative ductal carcinoma in situ cells in response to inflammatory stimuli

There are data to suggest that some ductal carcinoma in situ (DCIS) may evolve through an evolutionary bottleneck, where minor clones susceptible to the imposed selective pressure drive disease progression. Here, we tested the hypothesis that an impact of the inflammatory environment on DCIS evoluti...

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Detalhes bibliográficos
Publicado no:Neoplasia
Main Authors: Piasecka, Dominika, Braun, Marcin, Mieszkowska, Magdalena, Kowalczyk, Lukasz, Kopczynski, Janusz, Kordek, Radzislaw, Sadej, Rafal, Romanska, Hanna M.
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2020
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Original article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7522292/
https://ncbi.nlm.nih.gov/pubmed/32980776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2020.09.003
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