Heterologous Combination of ChAdOx1 and MVA Vectors Expressing Protein NS1 as Vaccination Strategy to Induce Durable and Cross-Protective CD8+ T Cell Immunity to Bluetongue Virus

The sequence of non-structural protein NS1 of bluetongue virus (BTV), which contains immunodominant CD8+ T cell epitopes, is highly conserved among BTV serotypes, and has therefore become a major tool in the development of a universal BTV vaccine. In this work, we have engineered multiserotype BTV v...

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Detalhes bibliográficos
Publicado no:Vaccines (Basel)
Main Authors: Utrilla-Trigo, Sergio, Jiménez-Cabello, Luis, Alonso-Ravelo, Ruymán, Calvo-Pinilla, Eva, Marín-López, Alejandro, Moreno, Sandra, Lorenzo, Gema, Benavides, Julio, Gilbert, Sarah, Nogales, Aitor, Ortego, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564706/
https://ncbi.nlm.nih.gov/pubmed/32610561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8030346
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