Protection of IFNAR (−/−) Mice against Bluetongue Virus Serotype 8, by Heterologous (DNA/rMVA) and Homologous (rMVA/rMVA) Vaccination, Expressing Outer-Capsid Protein VP2

The protective efficacy of recombinant vaccines expressing serotype 8 bluetongue virus (BTV-8) capsid proteins was tested in a mouse model. The recombinant vaccines comprised plasmid DNA or Modified Vaccinia Ankara viruses encoding BTV VP2, VP5 or VP7 proteins. These constructs were administered alo...

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Detalhes bibliográficos
Main Authors: Jabbar, Tamara Kusay, Calvo-Pinilla, Eva, Mateos, Francisco, Gubbins, Simon, Bin-Tarif, Abdelghani, Bachanek-Bankowska, Katarzyna, Alpar, Oya, Ortego, Javier, Takamatsu, Haru-Hisa, Mertens, Peter Paul Clement, Castillo-Olivares, Javier
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3625202/
https://ncbi.nlm.nih.gov/pubmed/23593251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0060574
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