CD8 T Cell Responses to an Immunodominant Epitope within the Nonstructural Protein NS1 Provide Wide Immunoprotection against Bluetongue Virus in IFNAR(−/−) Mice

The development of vaccines against bluetongue, a prevalent livestock disease, has been focused on surface antigens that induce strong neutralizing antibody responses. Because of their antigenic variability, these vaccines are usually serotype restricted. We now show that a single highly conserved n...

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Publicat a:J Virol
Autors principals: Marín-López, Alejandro, Calvo-Pinilla, Eva, Barriales, Diego, Lorenzo, Gema, Brun, Alejandro, Anguita, Juan, Ortego, Javier
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2018
Matèries:
Vaccines and Antiviral Agents
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6069212/
https://ncbi.nlm.nih.gov/pubmed/29875250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00938-18
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