Amyloid Beta Peptide (Aβ(1-42)) Reverses the Cholinergic Control of Monocytic IL-1β Release

Amyloid-β peptide (Aβ(1-42)), the cleavage product of the evolutionary highly conserved amyloid precursor protein, presumably plays a pathogenic role in Alzheimer’s disease. Aβ(1-42) can induce the secretion of the pro-inflammatory cytokine intereukin-1β (IL-1β) in immune cells within and out of the...

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Publicat a:J Clin Med
Autors principals: Richter, Katrin, Ogiemwonyi-Schaefer, Raymond, Wilker, Sigrid, Chaveiro, Anna I., Agné, Alisa, Hecker, Matthias, Reichert, Martin, Amati, Anca-Laura, Schlüter, Klaus-Dieter, Manzini, Ivan, Schmalzing, Günther, McIntosh, J. Michael, Padberg, Winfried, Grau, Veronika, Hecker, Andreas
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564705/
https://ncbi.nlm.nih.gov/pubmed/32906646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jcm9092887
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