β-Nicotinamide Adenine Dinucleotide (β-NAD) Inhibits ATP-Dependent IL-1β Release from Human Monocytic Cells

While interleukin-1β (IL-1β) is a potent pro-inflammatory cytokine essential for host defense, high systemic levels cause life-threatening inflammatory syndromes. ATP, a stimulus of IL-1β maturation, is released from damaged cells along with β-nicotinamide adenine dinucleotide (β-NAD). Here, we test...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Hiller, Sebastian Daniel, Heldmann, Sarah, Richter, Katrin, Jurastow, Innokentij, Küllmar, Mira, Hecker, Andreas, Wilker, Sigrid, Fuchs-Moll, Gabriele, Manzini, Ivan, Schmalzing, Günther, Kummer, Wolfgang, Padberg, Winfried, McIntosh, J. Michael, Damm, Jelena, Zakrzewicz, Anna, Grau, Veronika
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979475/
https://ncbi.nlm.nih.gov/pubmed/29642561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041126
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