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Cancer-Associated Fibroblast Mediated Inhibition of CD8+ Cytotoxic T Cell Accumulation in Tumours: Mechanisms and Therapeutic Opportunities

SIMPLE SUMMARY: The ability of the immune system to kill tumour cells is a natural and extremely effective defence mechanism for fighting cancer. Cytotoxic-T-cells are a critical component of our immune system which function is to eliminate cancer cells. In some cancers, especially those with a rich...

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Détails bibliographiques
Publié dans:Cancers (Basel)
Auteurs principaux: Freeman, Patrick, Mielgo, Ainhoa
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564636/
https://ncbi.nlm.nih.gov/pubmed/32967079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12092687
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