Neonatal Pig Sertoli Cells Survive Xenotransplantation by Creating an Immune Modulatory Environment Involving CD4 and CD8 Regulatory T Cells

The acute cell-mediated immune response presents a significant barrier to xenotransplantation. Immune-privileged Sertoli cells (SC) can prolong the survival of co-transplanted cells including xenogeneic islets, hepatocytes, and neurons by protecting them from immune rejection. Additionally, SC survi...

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Publicado en:Cell Transplant
Autores principales: Kaur, Gurvinder, Wright, Kandis, Mital, Payal, Hibler, Taylor, Miranda, Jonathan M., Thompson, Lea Ann, Halley, Katelyn, Dufour, Jannette M.
Formato: Artigo
Lenguaje:Inglês
Publicado: SAGE Publications 2020
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564626/
https://ncbi.nlm.nih.gov/pubmed/32841048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0963689720947102
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