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An overview of a Sertoli cell transplantation model to study testis morphogenesis and the role of the Sertoli cells in immune privilege

Advanced testicular germ cells, expressing novel cell surface and intracellular proteins, appear after the establishment of central tolerance and thus are auto-immunogenic. However, due to testis immune privilege these germ cells normally do not evoke a detrimental immune response. The Sertoli cell...

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Détails bibliographiques
Publié dans:Environ Epigenet
Auteurs principaux: Kaur, Gurvinder, Vadala, Scott, Dufour, Jannette M.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5804552/
https://ncbi.nlm.nih.gov/pubmed/29492314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eep/dvx012
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