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An overview of a Sertoli cell transplantation model to study testis morphogenesis and the role of the Sertoli cells in immune privilege

Advanced testicular germ cells, expressing novel cell surface and intracellular proteins, appear after the establishment of central tolerance and thus are auto-immunogenic. However, due to testis immune privilege these germ cells normally do not evoke a detrimental immune response. The Sertoli cell...

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Detalhes bibliográficos
Publicado no:Environ Epigenet
Main Authors: Kaur, Gurvinder, Vadala, Scott, Dufour, Jannette M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5804552/
https://ncbi.nlm.nih.gov/pubmed/29492314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eep/dvx012
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