Alterations in Progesterone Receptor Isoform Balance in Normal and Neoplastic Breast Cells Modulates the Stem Cell Population

To investigate the role of PR isoforms on the homeostasis of stem cells in the normal and neoplastic mammary gland, we used PRA and PRB transgenic mice and the T47D human breast cancer cell line and its derivatives, T47D YA and YB (manipulated to express only PRA or PRB, respectively). Flow cytometr...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Recouvreux, María Sol, Diaz Bessone, María Inés, Taruselli, Agustina, Todaro, Laura, Lago Huvelle, María Amparo, Sampayo, Rocío G., Bissell, Mina J., Simian, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564437/
https://ncbi.nlm.nih.gov/pubmed/32932770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9092074
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