A Replicating Single-Cycle Adenovirus Vaccine Effective against Clostridium difficile

Clostridium difficile causes nearly 500,000 infections and nearly 30,000 deaths each year in the U.S., which is estimated to cost $4.8 billion. C. difficile infection (CDI) arises from bacteria colonizing the large intestine and releasing two toxins, toxin A (TcdA) and toxin B (TcdB). Generating hum...

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Enregistré dans:
Détails bibliographiques
Publié dans:Vaccines (Basel)
Auteurs principaux: Matchett, William E., Anguiano-Zarate, Stephanie, Malewana, Goda Baddage Rakitha, Mudrick, Haley, Weldy, Melissa, Evert, Clayton, Khoruts, Alexander, Sadowsky, Michael, Barry, Michael A.
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7564163/
https://ncbi.nlm.nih.gov/pubmed/32842679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8030470
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