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The MAO Inhibitor Tranylcypromine Alters LPS- and Aβ-Mediated Neuroinflammatory Responses in Wild-type Mice and a Mouse Model of AD

Monoamine oxidase (MAO) has been implicated in neuroinflammation, and therapies targeting MAO are of interest for neurodegenerative diseases. The small-molecule drug tranylcypromine, an inhibitor of MAO, is currently used as an antidepressant and in the treatment of cancer. However, whether tranylcy...

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Опубликовано в: :Cells
Главные авторы: Park, HyunHee, Han, Kyung-Min, Jeon, Hyongjun, Lee, Ji-Soo, Lee, Hyunju, Jeon, Seong Gak, Park, Jin-Hee, Kim, Yu Gyung, Lin, Yuxi, Lee, Young-Ho, Jeong, Yun Ha, Hoe, Hyang-Sook
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2020
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563969/
https://ncbi.nlm.nih.gov/pubmed/32872335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9091982
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