High-speed single-molecule imaging reveals signal transduction by induced transbilayer raft phases

Using single-molecule imaging with enhanced time resolutions down to 5 ms, we found that CD59 cluster rafts and GM1 cluster rafts were stably induced in the outer leaflet of the plasma membrane (PM), which triggered the activation of Lyn, H-Ras, and ERK and continually recruited Lyn and H-Ras right...

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Bibliographic Details
Published in:J Cell Biol
Main Authors: Koyama-Honda, Ikuko, Fujiwara, Takahiro K., Kasai, Rinshi S., Suzuki, Kenichi G.N., Kajikawa, Eriko, Tsuboi, Hisae, Tsunoyama, Taka A., Kusumi, Akihiro
Format: Artigo
Language:Inglês
Published: Rockefeller University Press 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563750/
https://ncbi.nlm.nih.gov/pubmed/33053147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202006125
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