Tetravalent Immunogen Assembled from Conserved Regions of HIV-1 and Delivered as mRNA Demonstrates Potent Preclinical T-Cell Immunogenicity and Breadth

A vaccine will likely be one of the key tools for ending the HIV-1/AIDS epidemic by preventing HIV-1 spread within uninfected populations and achieving a cure for people living with HIV-1. The currently prevailing view of the vaccine field is to introduce protective antibodies, nevertheless, a vacci...

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Vydáno v:Vaccines (Basel)
Hlavní autoři: Moyo, Nathifa, Wee, Edmund G., Korber, Bette, Bahl, Kapil, Falcone, Samantha, Himansu, Sunny, Wong, Adrianne L., Dey, Antu K., Feinberg, Mark, Hanke, Tomáš
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563622/
https://ncbi.nlm.nih.gov/pubmed/32640600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines8030360
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