Cathepsin Inhibition Modulates Metabolism and Polarization of Tumor-Associated Macrophages

SIMPLE SUMMARY: Stroma-infiltrating tumor-associated macrophages (TAM) play an important role in regulating tumor progression and chemoresistance. Many tumor-infiltrating macrophage populations can be identified by preferential expression of distinct marker genes associated with an M2 phenotype and...

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Bibliographic Details
Published in:Cancers (Basel)
Main Authors: Oelschlaegel, Diana, Weiss Sadan, Tommy, Salpeter, Seth, Krug, Sebastian, Blum, Galia, Schmitz, Werner, Schulze, Almut, Michl, Patrick
Format: Artigo
Language:Inglês
Published: MDPI 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563557/
https://ncbi.nlm.nih.gov/pubmed/32927704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12092579
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