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Fully-Connected Neural Networks with Reduced Parameterization for Predicting Histological Types of Lung Cancer from Somatic Mutations

Several challenges appear in the application of deep learning to genomic data. First, the dimensionality of input can be orders of magnitude greater than the number of samples, forcing the model to be prone to overfitting the training dataset. Second, each input variable’s contribution to the predic...

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Detalhes bibliográficos
Publicado no:Biomolecules
Main Authors: Kobayashi, Kazuma, Bolatkan, Amina, Shiina, Shuichiro, Hamamoto, Ryuji
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563438/
https://ncbi.nlm.nih.gov/pubmed/32872133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10091249
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