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Deep convolutional neural networks for accurate somatic mutation detection

Accurate detection of somatic mutations is still a challenge in cancer analysis. Here we present NeuSomatic, the first convolutional neural network approach for somatic mutation detection, which significantly outperforms previous methods on different sequencing platforms, sequencing strategies, and...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Sahraeian, Sayed Mohammad Ebrahim, Liu, Ruolin, Lau, Bayo, Podesta, Karl, Mohiyuddin, Marghoob, Lam, Hugo Y. K.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6399298/
https://ncbi.nlm.nih.gov/pubmed/30833567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09027-x
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