Hypoxia Predicts Poor Prognosis in Neuroblastoma Patients and Associates with Biological Mechanisms Involved in Telomerase Activation and Tumor Microenvironment Reprogramming

The biological and clinical heterogeneity of neuroblastoma (NB) demands novel biomarkers and therapeutic targets in order to drive the most appropriate treatment for each patient. Hypoxia is a condition of low-oxygen tension occurring in poorly vascularized tumor tissues. In this study, we aimed to...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Cangelosi, Davide, Morini, Martina, Zanardi, Nicolò, Sementa, Angela Rita, Muselli, Marco, Conte, Massimo, Garaventa, Alberto, Pfeffer, Ulrich, Bosco, Maria Carla, Varesio, Luigi, Eva, Alessandra
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7563184/
https://ncbi.nlm.nih.gov/pubmed/32825087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12092343
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