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Unique Pharmacological Properties of the Kappa Opioid Receptor Signaling Through Gαz as Shown with Bioluminescence Resonance Energy Transfer
Opioid receptors (ORs) convert extracellular messages to signaling events by coupling to the heterotrimeric G proteins, Gα•βγ. Classic pharmacological methods, such as [(35)S]GTPγS binding and inhibition of cyclic AMP production, allow for general opioid characterization, but they are subject to the...
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| Publicado no: | Mol Pharmacol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7562983/ https://ncbi.nlm.nih.gov/pubmed/32958572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.120.119404 |
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