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Duodenal acidification induces gastric relaxation and alters epithelial barrier function by a mast cell independent mechanism

Duodenal hyperpermeability and low-grade inflammation in functional dyspepsia is potentially related to duodenal acid exposure. We aimed to evaluate in healthy volunteers the involvement of mast cell activation on the duodenogastric reflex and epithelial integrity during duodenal acidification. This...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Vanheel, Hanne, Vicario, Maria, Beeckmans, Dorien, Cocca, Silvia, Wauters, Lucas, Accarie, Alison, Toth, Joran, Rodewald, Hans-Reimer, De Hertogh, Gert, Matteoli, Gianluca, Boeckxstaens, Guy, Tack, Jan, Farre, Ricard, Vanuytsel, Tim
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7562901/
https://ncbi.nlm.nih.gov/pubmed/33060783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74491-1
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