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Analysis of gene expression from systemic lupus erythematosus synovium reveals myeloid cell-driven pathogenesis of lupus arthritis

Arthritis is a common manifestation of systemic lupus erythematosus (SLE) yet understanding of the underlying pathogenic mechanisms remains incomplete. We, therefore, interrogated gene expression profiles of SLE synovium to gain insight into the nature of lupus arthritis (LA), using osteoarthritis (...

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Foilsithe in:Sci Rep
Main Authors: Hubbard, Erika L., Catalina, Michelle D., Heuer, Sarah, Bachali, Prathyusha, Robl, Robert, Geraci, Nicholas S., Grammer, Amrie C., Lipsky, Peter E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group UK 2020
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7562741/
https://ncbi.nlm.nih.gov/pubmed/33060686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74391-4
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