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MED19 Regulates Adipogenesis and Maintenance of White Adipose Tissue Mass by Mediating PPARγ-Dependent Gene Expression

The Mediator complex relays regulatory signals from gene-specific transcription factors to the basal transcriptional machinery. However, the role of individual Mediator subunits in different tissues remains unclear. Here, we demonstrate that MED19 is essential for adipogenesis and maintenance of whi...

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Vydáno v:Cell Rep
Hlavní autoři: Dean, John M., He, Anyuan, Tan, Min, Wang, Jun, Lu, Dongliang, Razani, Babak, Lodhi, Irfan J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7561447/
https://ncbi.nlm.nih.gov/pubmed/33027649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108228
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