A Mucosal Adenovirus Prime/Systemic Envelope Boost Vaccine Regimen Elicits Responses in Cervicovaginal and Alveolar Macrophages of Rhesus Macaques Associated With Delayed SIV Acquisition and B Cell Help

Vaccine strategies targeting the mucosal portal of entry may prevent HIV acquisition and systemic infection. Macrophages in cervicovaginal compartments are one of the first cell types to encounter virus upon vaginal exposure. Their activation can lead to recruitment of additional macrophages and CD4...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Hunegnaw, Ruth, Helmold Hait, Sabrina, Enyindah-Asonye, Gospel, Rahman, Mohammad Arif, Ko, Eun-Ju, Hogge, Christopher J., Hoang, Tanya, Robert-Guroff, Marjorie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7561428/
https://ncbi.nlm.nih.gov/pubmed/33117363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.571804
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