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A Mucosal Adenovirus Prime/Systemic Envelope Boost Vaccine Regimen Elicits Responses in Cervicovaginal and Alveolar Macrophages of Rhesus Macaques Associated With Delayed SIV Acquisition and B Cell Help

Vaccine strategies targeting the mucosal portal of entry may prevent HIV acquisition and systemic infection. Macrophages in cervicovaginal compartments are one of the first cell types to encounter virus upon vaginal exposure. Their activation can lead to recruitment of additional macrophages and CD4...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Hunegnaw, Ruth, Helmold Hait, Sabrina, Enyindah-Asonye, Gospel, Rahman, Mohammad Arif, Ko, Eun-Ju, Hogge, Christopher J., Hoang, Tanya, Robert-Guroff, Marjorie
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7561428/
https://ncbi.nlm.nih.gov/pubmed/33117363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.571804
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