A Mucosal Adenovirus Prime/Systemic Envelope Boost Vaccine Regimen Elicits Responses in Cervicovaginal and Alveolar Macrophages of Rhesus Macaques Associated With Delayed SIV Acquisition and B Cell Help

Vaccine strategies targeting the mucosal portal of entry may prevent HIV acquisition and systemic infection. Macrophages in cervicovaginal compartments are one of the first cell types to encounter virus upon vaginal exposure. Their activation can lead to recruitment of additional macrophages and CD4...

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Vydáno v:Front Immunol
Hlavní autoři: Hunegnaw, Ruth, Helmold Hait, Sabrina, Enyindah-Asonye, Gospel, Rahman, Mohammad Arif, Ko, Eun-Ju, Hogge, Christopher J., Hoang, Tanya, Robert-Guroff, Marjorie
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2020
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7561428/
https://ncbi.nlm.nih.gov/pubmed/33117363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.571804
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