Overexpression of CD6 and PD-1 Identifies Dysfunctional CD8(+) T-Cells During Chronic SIV Infection of Rhesus Macaques

Effective CD8(+) T-cell responses play an important role in determining the course of SIV/HIV viral infection. Here we identified a unique population of dysfunctional CD8(+) T-cells in lymphoid tissues and bronchoalveolar lavage (BAL) of rhesus macaques with chronic SIV infection characterized by co...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Enyindah-Asonye, Gospel, Nwankwo, Anthony, Rahman, Mohammad Arif, Hunegnaw, Ruth, Hogge, Christopher, Helmold Hait, Sabrina, Ko, Eun-Ju, Hoang, Tanya, Robert-Guroff, Marjorie
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6961594/
https://ncbi.nlm.nih.gov/pubmed/31998302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.03005
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