Pharmacodynamics of glyburide, metformin and glyburide/metformin combination therapy in the treatment of gestational diabetes mellitus

In gestational diabetes mellitus (GDM), women are unable to compensate for the increased insulin resistance during pregnancy. Data are limited regarding the pharmacodynamic effects of metformin and glyburide during pregnancy. This study characterized insulin sensitivity (SI), β-cell responsivity, an...

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Vydáno v:Clin Pharmacol Ther
Hlavní autoři: Shuster, Diana L., Shireman, Laura M., Ma, Xiaosu, Shen, Danny D., Nichols, Shannon K. Flood, Ahmed, Mahmoud S., Clark, Shannon, Caritis, Steve, Venkataramanan, Raman, Haas, David M., Quinney, Sara K., Haneline, Laura S., Tita, Alan T., Manuck, Tracy A., Thummel, Kenneth E., Brown, Linda Morris, Ren, Zhaoxia, Brown, Zane, Easterling, Thomas R., Hebert, Mary F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7561209/
https://ncbi.nlm.nih.gov/pubmed/31869430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpt.1749
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