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TRPM7 channel activity in Jurkat T lymphocytes during magnesium depletion and loading: implications for divalent metal entry and cytotoxicity
TRPM7 is a cation channel-protein kinase highly expressed in T lymphocytes and other immune cells. It has been proposed to constitute a cellular entry pathway for Mg(2+) and divalent metal cations such as Ca(2+), Zn(2+), Cd(2+), Mn(2+)and Ni(2+). TRPM7 channels are inhibited by cytosolic Mg(2+), ren...
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| Publicado no: | Pflugers Arch |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7561021/ https://ncbi.nlm.nih.gov/pubmed/32964285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00424-020-02457-3 |
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