HIV/SIV DNA vaccine combined with protein in a co-immunization protocol elicits highest humoral responses to envelope in mice and macaques

Vaccination with HIV/SIV DNAs elicits potent T-cell responses. To improve humoral immune responses, we combined DNA and protein in a co-immunization protocol using in vivo electroporation in mice and macaques. DNA&protein co-immunization induced higher antibody responses than DNA or protein alon...

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Enregistré dans:
Détails bibliographiques
Publié dans:Vaccine
Auteurs principaux: Li, Jinyao, Valentin, Antonio, Kulkarni, Viraj, Rosati, Margherita, Beach, Rachel Kelly, Alicea, Candido, Hannaman, Drew, Reed, Steven G., Felber, Barbara K., Pavlakis, George N.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7561005/
https://ncbi.nlm.nih.gov/pubmed/23624057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2013.04.037
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