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Lifetime analysis of mdx skeletal muscle reveals a progressive pathology that leads to myofiber loss

The muscular dystrophy X-linked mouse (mdx) is the most commonly used preclinical model for Duchenne muscular dystrophy. Although disease progression in the mouse does not perfectly model the human disease, it shares many pathological features. Early characterizations of the model reported severe pa...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Massopust, Ryan T., Lee, Young il, Pritchard, Anna L., Nguyen, Van-Khoa M., McCreedy, Dylan A., Thompson, Wesley J.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560899/
https://ncbi.nlm.nih.gov/pubmed/33057110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74192-9
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