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Lifetime analysis of mdx skeletal muscle reveals a progressive pathology that leads to myofiber loss

The muscular dystrophy X-linked mouse (mdx) is the most commonly used preclinical model for Duchenne muscular dystrophy. Although disease progression in the mouse does not perfectly model the human disease, it shares many pathological features. Early characterizations of the model reported severe pa...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Massopust, Ryan T., Lee, Young il, Pritchard, Anna L., Nguyen, Van-Khoa M., McCreedy, Dylan A., Thompson, Wesley J.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560899/
https://ncbi.nlm.nih.gov/pubmed/33057110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74192-9
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