Dermal fibroblasts have different extracellular matrix profiles induced by TGF-β, PDGF and IL-6 in a model for skin fibrosis

Different stimulants might induce different extracellular matrix profiles. It is essential to gain an understanding and quantification of these changes to allow for focused anti-fibrotic drug development. This study investigated the expression of extracellular matrix by dermal fibroblast mimicking f...

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Udgivet i:Sci Rep
Main Authors: Juhl, Pernille, Bondesen, Sandie, Hawkins, Clare Louise, Karsdal, Morten Asser, Bay-Jensen, Anne-Christine, Davies, Michael Jonathan, Siebuhr, Anne Sofie
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560847/
https://ncbi.nlm.nih.gov/pubmed/33057073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74179-6
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