Matrix Metalloproteinase-dependent turnover of cartilage, synovial membrane, and connective tissue is elevated in rats with collagen induced arthritis

BACKGROUND: Rheumatoid arthritis is a disease affecting the extracellular matrix of especially synovial joints. The thickness of the synovial membrane increases and surrounding tissue degrades, leading to altered collagen balance in the tissues. In this study, we investigated the altered tissue bala...

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Autori principali: Siebuhr, Anne Sofie, Wang, Jianxia, Karsdal, Morten, Bay-Jensen, Anne-C, Y, Jin, Q, Zheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551788/
https://ncbi.nlm.nih.gov/pubmed/22992383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-10-195
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