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Matrix Metalloproteinase-dependent turnover of cartilage, synovial membrane, and connective tissue is elevated in rats with collagen induced arthritis

BACKGROUND: Rheumatoid arthritis is a disease affecting the extracellular matrix of especially synovial joints. The thickness of the synovial membrane increases and surrounding tissue degrades, leading to altered collagen balance in the tissues. In this study, we investigated the altered tissue bala...

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Detalhes bibliográficos
Main Authors: Siebuhr, Anne Sofie, Wang, Jianxia, Karsdal, Morten, Bay-Jensen, Anne-C, Y, Jin, Q, Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3551788/
https://ncbi.nlm.nih.gov/pubmed/22992383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-10-195
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