Using whole-exome sequencing and protein interaction networks to prioritize candidate genes for germline cutaneous melanoma susceptibility

Although next-generation sequencing has demonstrated great potential for novel gene discovery, confirming disease-causing genes after initial discovery remains challenging. Here, we applied a network analysis approach to prioritize candidate genes identified from whole-exome sequencing analysis of 9...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Yepes, Sally, Tucker, Margaret A., Koka, Hela, Xiao, Yanzi, Jones, Kristine, Vogt, Aurelie, Burdette, Laurie, Luo, Wen, Zhu, Bin, Hutchinson, Amy, Yeager, Meredith, Hicks, Belynda, Freedman, Neal D., Chanock, Stephen J., Goldstein, Alisa M., Yang, Xiaohong R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560829/
https://ncbi.nlm.nih.gov/pubmed/33057211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74293-5
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge