Using whole-exome sequencing and protein interaction networks to prioritize candidate genes for germline cutaneous melanoma susceptibility

Although next-generation sequencing has demonstrated great potential for novel gene discovery, confirming disease-causing genes after initial discovery remains challenging. Here, we applied a network analysis approach to prioritize candidate genes identified from whole-exome sequencing analysis of 9...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Rep
Main Authors: Yepes, Sally, Tucker, Margaret A., Koka, Hela, Xiao, Yanzi, Jones, Kristine, Vogt, Aurelie, Burdette, Laurie, Luo, Wen, Zhu, Bin, Hutchinson, Amy, Yeager, Meredith, Hicks, Belynda, Freedman, Neal D., Chanock, Stephen J., Goldstein, Alisa M., Yang, Xiaohong R.
פורמט: Artigo
שפה:Inglês
יצא לאור: Nature Publishing Group UK 2020
נושאים:
Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560829/
https://ncbi.nlm.nih.gov/pubmed/33057211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74293-5
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