Using whole-exome sequencing and protein interaction networks to prioritize candidate genes for germline cutaneous melanoma susceptibility

Although next-generation sequencing has demonstrated great potential for novel gene discovery, confirming disease-causing genes after initial discovery remains challenging. Here, we applied a network analysis approach to prioritize candidate genes identified from whole-exome sequencing analysis of 9...

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Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Yepes, Sally, Tucker, Margaret A., Koka, Hela, Xiao, Yanzi, Jones, Kristine, Vogt, Aurelie, Burdette, Laurie, Luo, Wen, Zhu, Bin, Hutchinson, Amy, Yeager, Meredith, Hicks, Belynda, Freedman, Neal D., Chanock, Stephen J., Goldstein, Alisa M., Yang, Xiaohong R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2020
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560829/
https://ncbi.nlm.nih.gov/pubmed/33057211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74293-5
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