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Specific cyprinid HIF isoforms contribute to cellular mitochondrial regulation

Hypoxia-inducible factor 1 (HIF-1) functions as a master regulator of the cellular response to hypoxic stress. Two HIF-1α paralogs, HIF-1αA and HIF-1αB, were generated in euteleosts by the specific, third round of genome duplication, but one paralog was later lost in most families with the exception...

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Publicado en:Sci Rep
Autores principales: Chen, Jing, Guan, Lihong, Zou, Ming, He, Shunping, Li, Dapeng, Chi, Wei
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560723/
https://ncbi.nlm.nih.gov/pubmed/33057104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-74210-w
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