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Mitochondrial phosphatase PGAM5 modulates cellular senescence by regulating mitochondrial dynamics
Mitochondria undergo dynamic fusion/fission, biogenesis and mitophagy in response to stimuli or stresses. Disruption of mitochondrial homeostasis could lead to cell senescence, although the underlying mechanism remains unclear. We show that deletion of mitochondrial phosphatase PGAM5 leads to accele...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7242393/ https://ncbi.nlm.nih.gov/pubmed/32439975 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16312-7 |
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