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A single dose of estrogen during hemorrhagic shock protects against Kidney Injury whereas estrogen restoration in ovariectomized mice is ineffective

The protective effect of estrogens against chronic glomerular diseases is admitted but remains debated during acute kidney injury (AKI). Using a model of resuscitated hemorrhagic shock in C57/Bl6 female mice, this study evaluated at 1 and 21 days the renal effect of (1) endogenous estrogen, using ov...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Buléon, Marie, Cuny, Mélodie, Grellier, Jimmy, Charles, Pierre-Yves, Belliere, Julie, Casemayou, Audrey, Arnal, Jean-François, Schanstra, Joost-Peter, Tack, Ivan
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560623/
https://ncbi.nlm.nih.gov/pubmed/33057080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73974-5
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