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Centromeres: genetic input to calibrate an epigenetic feedback loop

Centromeres are chromatin domains maintained by a self‐templating feedback loop based on nucleosomes bearing the histone H3 variant CENP‐A. The underlying centromeric DNA sequence is largely dispensable, yet paradoxically, it has highly conserved features. Hoffmann et al (2020) now uncover that when...

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Detalles Bibliográficos
Publicado en:EMBO J
Main Authors: van den Berg, Sebastiaan JW, Jansen, Lars ET
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7560195/
https://ncbi.nlm.nih.gov/pubmed/32959893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106638
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