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Molecular Crystal Forms of Antitubercular Ethionamide with Dicarboxylic Acids: Solid-State Properties and a Combined Structural and Spectroscopic Study

We report on the preparation, characterization, and bioavailability properties of three new crystal forms of ethionamide, an antitubercular agent used in the treatment of drug-resistant tuberculosis. The new adducts were obtained by combining the active pharmaceutical ingredient with three dicarboxy...

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Detalhes bibliográficos
Publicado no:Pharmaceutics
Main Authors: Bordignon, Simone, Cerreia Vioglio, Paolo, Amadio, Elena, Rossi, Federica, Priola, Emanuele, Voinovich, Dario, Gobetto, Roberto, Chierotti, Michele R.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7559828/
https://ncbi.nlm.nih.gov/pubmed/32872201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12090818
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