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Zinc Binding by Histatin 5 Promotes Fungicidal Membrane Disruption in C. albicans and C. glabrata

Histatin 5 (Hst 5) is an antimicrobial peptide produced in human saliva with antifungal activity for opportunistic pathogen Candida albicans. Hst 5 binds to multiple cations including dimerization-inducing zinc (Zn(2+)), although the function of this capability is incompletely understood. Hst 5 is t...

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Bibliografische gegevens
Gepubliceerd in:J Fungi (Basel)
Hoofdauteurs: Norris, Hannah L., Kumar, Rohitashw, Ong, Chih Yean, Xu, Ding, Edgerton, Mira
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2020
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7559477/
https://ncbi.nlm.nih.gov/pubmed/32751915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/jof6030124
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