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Candida albicans Flu1-Mediated Efflux of Salivary Histatin 5 Reduces Its Cytosolic Concentration and Fungicidal Activity

Histatin 5 (Hst 5) is a salivary human antimicrobial peptide that is toxic to the opportunistic yeast Candida albicans. Fungicidal activity of Hst 5 requires intracellular translocation and accumulation to a threshold concentration for it to disrupt cellular processes. Previously, we observed that t...

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Bibliografische gegevens
Hoofdauteurs: Li, Rui, Kumar, Rohitashw, Tati, Swetha, Puri, Sumant, Edgerton, Mira
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623299/
https://ncbi.nlm.nih.gov/pubmed/23380720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02295-12
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