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Understanding the Half-Life Extension of Intravitreally Administered Antibodies Binding to Ocular Albumin
The burden associated with frequent injections of current intravitreal (IVT) therapeutics may be reduced by long-acting delivery strategies. Binding to serum albumin has been shown to extend the ocular half-life in rabbits, however, the underlying molecular mechanisms and translational relevance rem...
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Publicado en: | Pharmaceutics |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
MDPI
2020
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7559355/ https://ncbi.nlm.nih.gov/pubmed/32858986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pharmaceutics12090810 |
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